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Pragmatic Play Free Trial

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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often characterized as focusing on practical aspects of design which include the recruitment process and consent, adhering and the use of standard equipment.

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A pragmatic trial that uses different investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is necessary for pragmatic trials to be valid and helps to reduce the chance of bias in the results. However excessive heterogeneity could lead to issues with the design of the trial.

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The purpose of pragmatic trials is to simulate real-life scenarios and gain maximum credibility externally. They are typically commissioned by policy makers and practitioners to aid in their decision-making. They are also a good method of determining the cause-effect relationship between the intervention and its effects. However, they should not be used as a substitute for explanatory studies.

The pragmatism idea is controversial and there are doubts about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which prove the validity of a clinical or physiological hypothesis as well as pragmatic trials, which inform the policy and practice of. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool tried to define the traits of a pragmatic research study, including recruitment, design, implementation of the intervention, and follow-up.

There is a growing trend in the number of pragmatic trials that are published. A recent Medline search using the terms naturalistic and pragmatic, limited to randomized controlled trials (RCTs), 프라그마틱 환수율 yielded 34 articles, as shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to remember that the majority of these studies were conducted in primary care settings.